Vaccine Innovation.
Beyond Convention.
We are dedicated to eliminating bacterial infections such as invasive pneumococcal disease, Group A Strep and periodontitis to protect every child born and every adult at risk across the globe.
Pushing the Boundaries of What’s Possible
Despite widespread vaccination with current pneumococcal conjugate vaccines (PCVs), there is an abundance of non-vaccine strains of the Streptococcus pneumoniae bacteria causing significant morbidity and mortality, underscoring the importance of advancing our lead program, VAX-24, a 24-valent PCV candidate. VAX-24 is currently the broadest-spectrum PCV in development and one of the most complex biologics ever created.
Re-Engineering How Vaccines are Made
We strive to overcome the limitations of conventional, cell-based vaccine approaches using advanced chemistry and modern synthetic techniques – including our XpressCF™ cell-free protein synthesis platform – to produce broad-spectrum vaccines that are uniquely capable of breaking down bacteria’s complex defense mechanisms while preserving immunogenicity.
Building a Pipeline of High-Fidelity and Broad-Spectrum Vaccines
Our PCV franchise is intended to improve upon existing pneumococcal vaccines by covering the serotypes responsible for most of the remaining pneumococcal disease currently in circulation. Following VAX-24, we are developing VAX-XP, a PCV candidate with an expanded breadth of coverage of greater than 30 strains of pneumococcal disease. Additional vaccine candidates in preclinical development target Group A Strep bacteria and periodontitis.
Latest News
01
Vaxcyte Reports Fourth Quarter and Full Year 2022 Financial Results and Provides Business Update
-- Company Received U.S. Food and Drug Administration (FDA) Clearance of VAX-24 Infant Investigational New Drug (IND) Application and Expects to Initiate Phase 2 Study in Second Quarter 2023 -- -- Topline Safety, Tolerability and Immunogenicity Results from VAX-24 Phase 2 Study in Adults 65 and
02
Vaxcyte Announces FDA Clearance of Investigational New Drug Application for VAX-24 for the Prevention of Invasive Pneumococcal Disease in Infants
-- Infant Phase 2 Study Initiation Expected in the Second Quarter of 2023, with Initial Topline Safety, Tolerability and Immunogenicity Data by 2025 -- -- Based on Positive Topline VAX-24 Phase 1/2 Proof-of-Concept Study Results in Adults, FDA Supported Initiation of Pediatric Program in Infants --
03
Vaxcyte to Report Fourth Quarter and Full Year 2022 Financial Results on February 27, 2023
SAN CARLOS, Calif., Feb. 16, 2023 (GLOBE NEWSWIRE) -- Vaxcyte, Inc. (Nasdaq: PCVX), a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, today announced that it will report financial results for the fourth
Careers: Built to Scale with Purpose
Looking for higher aspirations to ignite your mind and inspire your heart? Then join a team that brings grit and grace to the challenge of protecting every human from the consequences of endemic bacterial infections.